Document Type : Original Article
Authors
1
Oral and Maxillofacial Surgery Department, Faculty of Dentistry, Suez Canal University, Ismailia, Egypt
2
Oral and Maxillofacial surgery, Faculty of Dentistry, Suez Canal University, Ismailia, Egypt.
3
Department of Oral Radiology, Fcaulty of Dentistry, Suez Canal University
4
oral and Maxillofacial Surgery, Faculty of Dentistry, Suez Canal University, Ismailia, Egypt
Abstract
Introduction: Platelet Rich Fibrin (PRF) combined with Nanocrystalline
Hydroxyapatite bone graft offers a promising approach for enhancing bone
regeneration in maxillary bony defects. Aim: To evaluate postoperative clinical and
radiographic outcomes of maxillary intrabony defects using a mix of nanocrystalline
hydroxyapatite (nHA) bone graft with platelet rich fibrin (PRF) after removal of
maxillary cystic lesions. Materials and Methods: Sixteen patients necessitating the
surgical removal of intra-bony cystic lesions were enrolled in a randomized controlled
investigation and subsequently allocated to one of two study arms. Eight patients,
forming the control cohort (Group I), underwent conventional healing without the use
of grafting materials following surgical excision of the cystic lesions. In contrast, the
study cohort (Group II), also comprising eight patients, received a graft composed
of nanocrystalline hydroxyapatite and platelet-rich fibrin following lesion removal.
Results: Analysis of the collected data demonstrated a statistically significant lower
pain score in study group in the seventh day (p = 0.012). The study group showed a
more rapid resolution of edema compared to the control group, although differences
between groups at individual time points did not reach statistical significance (p =
1.000). Notably, the study group exhibited a highly statistically significant increase
in bone density at the T1 time interval compared to the control group (P < 0.001). In
contrast, baseline bone density measurements (T0) showed no statistically significant
disparity between the two groups (P = 0.466). No Postoperative complications for both
groups as infection, wound dehiscence, or looseness of adjacent teeth at 1-, 7-, and
14-days post-operative.
Conclusion: PRF combined with nanocrystalline hydroxyapatite may be considered
a potential material for promoting bone repair following the enucleation of maxillary
cystic lesions.
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