Role of Nano-Bioceramic Bone Graft on the Healing Process of Unfavorable Mandibular Angle Fracture (An experimental study)

Document Type : Original Article

Authors

1 Oral and Maxillofacial Surgery Faculty of Dentistry, Suez Canal University

2 oral and maxillofacial surgery department,faculty of dentistry,suez canal university

3 Professor of Surgery, Anesthesiology, and Radiology, Faculty of Veterinary, Suez Canal University, Egypt.

4 Professor of Inorganic Chemistry, Faculty of Science, Suez Canal University, Egypt.

5 Professor of Oral and Maxillofacial Surgery, Faculty of Dentistry, Suez Canal University, Egypt.

Abstract

Introduction: The most frequent fracture is a mandibular angle fracture, which
is challenging to treat because there is no established universal technique. So, for
diverse implant systems, different kinds of plates have been developed. Aim: This
study aimed to evaluate of nano bio-ceramic bone graft with 3D bone plate on the
healing of unfavorable mandibular angle fracture. Material and methods: This study
included 18 male adult mongrel dogs, animals were divided into (9 of each): study
group (I) where the angle fracture treated by 3 dimension bone plate with Nano bio
glass bone graft. Control group (II) where the angle fracture treated by 3 dimension
bone plate only. Noncritical size bone defects (3 mm diameter) were created in the
mandibular angle of the dogs. Bone density was measured in the vicinity of the
fracture line using the cone beam (CBCT). Results: Dogs were euthanized at 3, 6 and
12 weeks postoperatively, six dogs at a time, three dogs from each group. All of the 18
fracture line healed uneventfully. Soft tissue healing normally proceeded without any
signs of infection. Post-operative assessment of the current study revealed no obvious
complications; neither post-operative infection nor wound dehiscence was detected in
any case. The synthetic Nano bio glass bone graft was bio compatible and non- allergic.
CBCT showed that measurements of the bone density reading were increased in study
group more than control group throughout showing highly significantly reading after
12 weeks. The measurements of the bone density were higher in the study group than
control group throughout the whole study intervals. Conclusion: 3D Titanium plates
have superior biomechanical properties and biocompatibility when used in treatment of
fractures of the angle. Nano bio glass bone graft is a compatible material and doesn’t
interfere with the healing process of fracture filed.

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Dental Science Updates
Volume 5, Issue 1
March 2024
Pages 167-175

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